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2 hurt in crash at Orange Avenue, Plantation Road intersection

ROANOKE, Va. – UPDATE: All lanes of Orange Avenue NE are now open.

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A serious crash that sent two people to the hospital is causing a traffic issue at a busy intersection in Roanoke. 

Police responded to the crash at the intersection of Orange Avenue and Plantation Road around 6:15 a.m. Tuesday. A tractor-trailer and car collided there.

The driver and passenger of the car were taken to Carilion Roanoke Memorial Hospital. It's not clear yet how badly they were hurt. 

The intersection of Orange Avenue and Plantation Road is closed in the northeast section of the city. All westbound lanes of Orange Avenue are closed in that area. There is no estimate for when those lanes may reopen.

Hollins Road is open and can be used as a detour. Drivers can also use Pocahontas Avenue or Kimball Avenue. 

Investigators are at the scene trying to determine what led up to the wreck. 

This is a developing story. We're working to get more details.