Patrick Mahomes threw for 360 yards and five touchdowns, lifting the Kansas City Chiefs to an impressive 44-21 road win over the Arizona Cardinals in the opener for both teams.

Matthew Stafford threw for 287 yards and three touchdowns, Cooper Kupp and Odell Beckham Jr. each caught a touchdown pass and the Los Angeles Rams held on for a 30-23 win over the Arizona Cardinals.

James Conner ran for two touchdowns and caught a 45-yard TD pass from backup quarterback Colt McCoy as the short-handed Arizona Cardinals beat the San Francisco 49ers 31-17.

Byron Murphy intercepted two passes, including one he returned for a touchdown following a botched trick play, and the Arizona Cardinals rallied to beat the skidding Jacksonville Jaguars 31-19 on Sunday.

Chad Henne and rookie Shane Buechele threw touchdown passes to help the Kansas City Chiefs beat the Arizona Cardinals 17-10 in a preseason game Friday night.

Coupled with Tampa Bay’s 26-14 win over Minnesota (6-7), the Cardinals are back in a wild-card berth. we have to go out there and execute,” said Murray, who ran 10 times for 47 yards. “I don’t think we have any kind of a hangover from going out to Seattle last week," Giants coach Joe Judge said. The D limited New York to 159 yards in making Jones' return from a one-game absence with a hamstring injury miserable. The first one was set up by a 24-yard punt return by Christian Kirk to the Giants 38.